"Patients with true GACNS, proven by biopsy, invariably require aggressive therapy with drugs such as high doses of glucocorticoids (a cortisone-like drug such as Prednisone) and a second drug known as cyclophosphamide. These drugs are generally administered for six to twelve months and require meticulous follow-up to assess benefit and avoid side effects.
Possible side effects of high doses of glucocorticoids include abnormalities of blood sugar, blood pressure, weight gain, thinning of the bones, and increased risk of infections.
Cyclosphosphamide also has formidable toxicities including lowering of the white blood cells making individuals more prone to infections, bleeding from the bladder and even bladder cancer. Patients who take cyclophosphamide for more prolonged periods of time have a higher incidence of certain forms of cancer later in life."
This is not to be taken lightly. Dad will either start recovery due to these high dosages or die due to the high dosages.
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